Biologically, susceptibility to depression can be inherited,
so some types of depression run in families. This is often with especially with
bipolar disorder or maniac depression.
Investigation into families in which members develop bipolar disorder
shows that those with this condition will have a genetic makeup to an extent
than those who do not become ill.
Nevertheless, the reverse is not usually true. Which means
not everybody that have the genetic makeup that cause susceptibility to maniac
depression or bipolar disorder will have the illness. A stressful environment
can trigger bipolar disorder.
Major depression can run in families generation after
generation, though is not as powerful as bipolar disorder. People who do not
have family history of depression can also experience major depression.
Episodes of depression may be triggered by these external occurrences:
financial problem, serious loss, difficult relationship, not welcomed changes
in life pattern. Environmental, genetic and psychological factors can also
trigger episode of depression. These factors may cause depression in some
people more than others depending on how individuals respond to depression. For
example, people that are discriminated suffers depression more and also people
of socioeconomic disadvantage will have increased rate of depression more than
their advantage counterparts. Men appears to be prone to depression due to
unemployment effects, low socioeconomic status, and divorce. Women who has been emotionally, physically or
sexually abused, both as a child or by their partner are susceptible to
developing a depressive disorder also. Homosexuals are also prone to developing
depressive disorder when they start lacking a domestic partner.
Certain medications are also more likely to cause depression
mainly as a side effect. Such medications include medications used in the
treatment of: blood pressure, cancer, seizures, chronic pain, and contraceptive
drugs can cause depression. Some drugs used in treating psychiatric problems,
medications that treats insomnia and anxiety can add in development of
depression.
A number of mental health conditions and disabilities are also
connected depression. Depression also appear to be associated with changes in
brain serotonin and norepinephrine systems. These abnormalities does not cause
depressive disorders rather they are associated with depressive disorders.
Women are twice more likely to suffer depression than men.
According to research, it appears that stress due to
maternity during pregnancy can result in rise in the chances that the child
will be predispose depression as an adult, especially when there has been a
genetic susceptibility. The mother’s circulating stress hormone can affect the
development of the child’s brain during pregnancy. This will alter the fetus’
brain development thereby making the child to be prone to the risk of
depression later in adulthood. There is
an ongoing research to describe how this happens.
Treatment of depressive disorders.
Different racial groups have the ways they react to
treatment of depression and different side effects than others.
Antidepressant medications include:
Selective serotonin reuptake inhibitors (SSRIs). These are
medications which increases the level of neurochemical serotonin in the brain.
Recall. Low brain serotonin level indicates depression. This drugs works by
inhibition of serotonin uptake in the brain. The side effects include:
diarrhea, agitation, nausea, insomnia, and headache. The side effects are
usually mild. After the first month of usage these side effects will go away.
Dual-action antidepressant. These medications include:
duloxetine (cymbalta), venlafaxine (effexor) and desvenlafaxine (pristiq).
These medications are effective especially in treating severe and chronic
depressive disorders.
Mirtazapine (remeron). It works in a different way from
other types of drugs. The side effect is that it causes drowsiness. It is
normally advised to be taken at night-time especially for people who suffer
from insomnia.
Typical antidepressants. These include: nefazodone (serzone),
and trazodone (desyrel). They can increase the level of some neurochemicals in
the brain synapses and are effective in treating depression in many people.
Antipsychotic medicaitons. Which include: ziprasidone
(geodon), quetipine (seroquel), and paliperidone (invega). They are effective
in stabilizing moods and at times used in treating bipolar disorder, but must
be combined with other antidepressants.
Electroconvulsive therapy (ECT). This involves passing
electric current through the brain to produce controlled convulsions or
seizures. It is used in cases where the patient is not responding to
antidepressant drugs and also when a patient wants to commit suicide. ECT can
stop depression even after one or two weeks of using it. It is usually done
under anesthesia so people won’t feel much pain. Side effects include:
short-term memory loss that resolves rapidly.
Psychotherapies. This involves: to help patients find
solution to their problems and also gain insights into their problems; helping
the patient to change their negative ways of behaving and thinking that is
connected to depression.
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